WD40 DOMAIN DIVERGENCE IS IMPORTANT FOR FUNCTIONAL DIFFERENCES BETWEEN THE FISSION YEAST TUP11 AND TUP12 CO-REPRESSOR PROTEINS.

WD40 domain divergence is important for functional differences between the fission yeast Tup11 and Tup12 co-repressor proteins.

We have previously demonstrated that subsets of Ssn6/Tup target genes have distinct requirements for the Schizosaccharomyces pombe homologs Combination Oven Accessories of the Tup1/Groucho/TLE co-repressor proteins, Tup11 and Tup12.The very high level of divergence in the histone interacting repression domains of the two proteins suggested that det

read more

Systemic necrosis induced by overexpression of wheat yellow mosaic virus 14K suppresses the replication of other viruses in Nicotiana benthamiana

Abstract Systemic necrosis, induced by plant virus-derived elicitors, is considered as one of the most severe symptoms.It has never been reported that the elicitors encoded by wheat yellow mosaic virus (WYMV) can induce systemic necrosis in plant.In this study, we discovered that the WYMV-encoded 14K protein localized to the endoplasmic reticulum (

read more